Senior/Staff Mechanical Engineer

Company: Menlo Ventures
Location: Redwood City
Posted on: March 29, 2025

Job Description:

Synthego is a pioneering force in the biotechnology industry, dedicated to advancing the frontiers of CRISPR cell and gene therapies through cutting-edge CRISPR technology and expertise.We are looking to add a Senior or Staff Mechanical Engineer to our hardware & research team. In this role you will design, develop, and improve proprietary hardware for Synthego's CRISPR guide RNA manufacturing business.This is an exciting opportunity to gain experience in chemical process automation, mechanical design, data analysis, and product development. The ideal candidate is a collaborative, detail-oriented, and creative engineer who is interested in working with a talented team to push the boundaries of oligonucleotide manufacturing.What You'll Do:

• Design, prototype, and test mechanical systems involving multi-domain engineering in motion, fluidics, heat transfer, optical and electromechanical systems.
• Independently drive experiments according to sound engineering principles, business standards and procedures, and program requirements. Build testing set-ups, conduct experiments, analyze data, interpret results, and suggest follow-up experiments.
• Communicate designs and project updates through design reviews and presentations to executives, product stakeholders, and colleagues.
• Work cross-functionally to solve problems at the intersection of hardware and software engineering, chemistry, and data science.
• Maintain detailed and organized documentation including design history files, qualification records, and engineering drawings.About You:
  • For Senior leveling: B.S./M.S. in Mechanical Engineering or related field with 3-6 years of professional experience, or PhD with relevant project experience.
  • For Staff leveling: B.S./M.S. in Mechanical Engineering or related field with 6-9 years of professional experience, or PhD with relevant project experience.
  • Demonstrated track record of building mechanical systems involving fluid handling.
  • High proficiency with 3D CAD (SolidWorks preferred).
  • Basic programming proficiency with Python or similar.
  • Strong knowledge of design-for-manufacturing and GD&T principles.
  • Strong written and verbal communication skills.
  • Excellent problem-solving skills.
  • Able to multi-task and prioritize work effectively.Nice to Haves:
    • Demonstrated track record of building capital equipment including instruments and/or industrial automation systems in the life sciences or a similar industry (semiconductor, petrochemical, etc).
    • Experience with PLC programming.
    • Experience with chemical reactor design and scaling analysis.
    • Experience with high pressure equipment, oligonucleotide synthesis, and/or analytical instrumentation.
    • Knowledge of chemistry and/or previous experience working with oligonucleotides (DNA or RNA).
    • Proficiency with data analysis using Pandas/Scipy/Matplotlib or similar.
    • Machine shop experience.Company Perks & Benefits:
      • Equity options.
      • Medical, dental, and vision benefits.
      • 401k Program.
      • Catered meals on Tuesday and Thursday.
      • Paid parental leave.
      • Flexible paid time off.
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Keywords: Menlo Ventures, Redwood City , Senior/Staff Mechanical Engineer, Engineering , Redwood City, California